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  • Modern Biophysical Chemistry : Detection and Analysis of Biomolecules
    Modern Biophysical Chemistry : Detection and Analysis of Biomolecules

    This updated and up-to-date version of the first edition continues with the really interesting stuff to spice up a standard biophysics and biophysical chemistry course.All relevant methods used in current cutting edge research including such recent developments as super-resolution microscopy and next-generation DNA sequencing techniques, as well as industrial applications, are explained.The text has been developed from a graduate course taught by the author for several years, and by presenting a mix of basic theory and real-life examples, he closes the gap between theory and experiment. The first part, on basic biophysical chemistry, surveys fundamental and spectroscopic techniques as well as biomolecular properties that represent the modern standard and are also the basis for the more sophisticated technologies discussed later in the book.The second part covers the latest bioanalytical techniques such as the mentioned super-resolution and next generation sequencing methods, confocal fluorescence microscopy, light sheet microscopy, two-photon microscopy and ultrafast spectroscopy, single molecule optical, electrical and force measurements, fluorescence correlation spectroscopy, optical tweezers, quantum dots and DNA origami techniques.Both the text and illustrations have been prepared in a clear and accessible style, with extended and updated exercises (and their solutions) accompanying each chapter. Readers with a basic understanding of biochemistry and/or biophysics will quickly gain an overview of cutting edge technology for the biophysical analysis of proteins, nucleic acids and other biomolecules and their interactions.Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented.Questions of differing complexity testing the reader's understanding can be found at the end of each chapter with clearly described solutions available on the Wiley-VCH textbook homepage under: www.wiley-vch.de/textbooks

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  • Raman Scattering on Emerging Semiconductors and Oxides
    Raman Scattering on Emerging Semiconductors and Oxides

    Raman Scattering on Emerging Semiconductors and Oxides presents Raman scattering studies.It describes the key fundamental elements in applying Raman spectroscopies to various semiconductors and oxides without complicated and deep Raman theories. Across nine chapters, it covers:• SiC and IV-IV semiconductors,• III-GaN and nitride semiconductors,• III-V and II-VI semiconductors,• ZnO-based and GaO-based semiconducting oxides,• Graphene, ferroelectric oxides, and other emerging materials,• Wide-bandgap semiconductors of SiC, GaN, and ZnO, and• Ultra-wide gap semiconductors of AlN, Ga2O3, and graphene. Key achievements from the author and collaborators in the above fields are referred to and cited with typical Raman spectral graphs and analyses.Written for engineers, scientists, and academics, this comprehensive book will be fundamental for newcomers in Raman spectroscopy. Zhe Chuan Feng has had an impressive career spanning many years of important work in engineering and tech, including as a professor at the Graduate Institute of Photonics & Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei; establishing the Science Exploring Lab; joining Kennesaw State University as an adjunct professor, part-time; and at the Department of Electrical and Computer Engineering, Southern Polytechnic College of Engineering and Engineering Technology.Currently, he is focusing on materials research for LED, III-nitrides, SiC, ZnO, other semiconductors/oxides, and nanostructures and has devoted time to materials research and growth of III-V and II-VI compounds, LED, III nitrides, SiC, ZnO, GaO, and other semiconductors/oxides. Professor Feng has also edited and published multiple review books in his field, alongside authoring scientific journal papers and conference/proceeding papers.He has organized symposiums and been an invited speaker at different international conferences and universities.He has also served as a guest editor for special journal issues.

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  • Solvation Effects on Molecules and Biomolecules : Computational Methods and Applications
    Solvation Effects on Molecules and Biomolecules : Computational Methods and Applications

    The incessant development of quantum chemistry since the appearance of the Schrodinger ¨ equation has turned this area into a respectable branch of science with unprecedented capabilities.It is now a well-recognized eld of research with pred- tive power that is an important component in physical–chemical laboratories.Very important developments were conducted in the early days by bright theoretical s- entists that were ready to absorb the incredible and unpredicted computer revolution which was only just beginning.Isolated medium-size molecular systems can now be accurately studied theoretically by quantum chemical methods.However, it was also long recognized that all biomolecular phenomena necessary to obtain and sustain living systems take place in solution, as well as the vast majority of chemical p- cesses.Indeed solvent and liquid systems are germane in chemistry experiments.In physics, aconstant concern isthedescription of theroleplayed by theenvironment in modifying the properties of the system as compared to the isolated situation.Hence, the importance of studying atoms, molecules and biomolecules in the solvent en- ronment can hardly be denied.The quantum chemical studies of molecular systems affected by the interaction with a solvent had its own turning point before the end of the 1970s, when some pioneering work was done, including the dielectric pr- erties of the medium in an effective nonlinear Hamiltonian.This naturally led to the development of the so-called continuum models that are important and now popular.Continuum models can be implemented from the simplest to the most sophisticated quantum chemical methods.

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  • Applied Raman Spectroscopy : Concepts, Instrumentation, Chemometrics, and Life Science Applications
    Applied Raman Spectroscopy : Concepts, Instrumentation, Chemometrics, and Life Science Applications

    Applied Raman Spectroscopy: Concepts, Instrumentation, Chemometrics, and Life Science Applications synthesizes recent developments in the field, providing an updated overview.The book focuses on the modern concepts of Raman spectroscopy techniques, recent technological innovations, data analysis using chemometric methods, along with the latest examples of life science applications relevant in academia and industries.It will be beneficial to researchers from various branches of science and technology, and it will point them to modern techniques coupled with data analysis methods.In addition, it will help instruct new readers on Raman spectroscopy and hyphenated Raman spectroscopic techniques. The book is primarily written for analytical and physical chemistry students and researchers at a more advanced level who require a broad introductory overview of the applications of Raman spectroscopy, as well as those working in applied industry and clinical laboratories.Students, researchers, and industry workers in related fields, including X-ray and materials science, agriculture, botany, molecular biology and biotechnology, mineralogy, and environmental science will also find it very useful.

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  • What is the significance of biomolecules for the human organism?

    Biomolecules are essential for the human organism as they serve as the building blocks of life. They are involved in various biological processes such as metabolism, energy production, and cell structure. Proteins, carbohydrates, lipids, and nucleic acids are all examples of biomolecules that play crucial roles in maintaining the body's functions. Without these biomolecules, the human organism would not be able to survive or function properly. Therefore, understanding the significance of biomolecules is essential for understanding the complexities of human biology and health.

  • Where has photonics gone?

    Photonics has advanced and expanded into various industries and applications, including telecommunications, healthcare, manufacturing, and defense. It has enabled the development of faster and more efficient communication systems, medical imaging technologies, high-precision manufacturing tools, and advanced military equipment. Photonics has also made significant contributions to renewable energy technologies, such as solar cells and LED lighting. Overall, photonics has become an integral part of modern technology and continues to drive innovation in a wide range of fields.

  • How advanced is nanotechnology?

    Nanotechnology is a rapidly advancing field that involves manipulating materials at the nanoscale, which is on the order of billionths of a meter. It has already led to significant advancements in various industries, including medicine, electronics, and materials science. Researchers are continually developing new techniques and applications for nanotechnology, such as targeted drug delivery, nanoelectronics, and nanomaterials with unique properties. While nanotechnology is still in its early stages, it holds great promise for revolutionizing many aspects of our lives in the future.

  • What is NMR spectroscopy?

    Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique used to study the structure and dynamics of molecules. It provides detailed information about the chemical environment, connectivity, and conformation of atoms within a molecule. By measuring the interactions of atomic nuclei with a magnetic field, NMR spectroscopy can elucidate the molecular structure of organic compounds, proteins, and other biomolecules. This technique is widely used in chemistry, biochemistry, and structural biology for research and drug discovery purposes.

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  • Chemical Theory and Multiscale Simulation in Biomolecules : From Principles to Case Studies
    Chemical Theory and Multiscale Simulation in Biomolecules : From Principles to Case Studies

    Chemical Theory and Multiscale Simulation in Biomolecules: From Principles to Case Studies helps readers understand what simulation is, what information modeling of biomolecules can provide, and how to compare this information with experiments.Beginning with an introduction to computational theory for modeling, the book goes on to describe how to control the conditions of modeling systems and possible strategies for time-cost savings in computation.Part Two further outlines key methods, with step-by-step guidance supporting readers in studying and practicing simulation processes.Part Three then shows how these theories are controlled and applied in practice, through examples and case studies on varied applications. This book is a practical guide for new learners, supporting them in learning and applying molecular modeling in practice, whilst also providing more experienced readers with the knowledge needed to gain a deep understanding of the theoretical background behind key methods.

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  • Nanomaterials-Based Sensing Platforms : Towards the Efficient Detection of Biomolecules and Gases
    Nanomaterials-Based Sensing Platforms : Towards the Efficient Detection of Biomolecules and Gases

    Sensors are effective tools used to carry out cost-effective, fast, and reliable sensing for a wide range of applications.This volume presents a brief history behind sensing technology and highlights a broad range of biosensing techniques based on optical and electrochemical response methods.Starting from the traditional enzyme-based biosensing method to functionalized nanostructure-based sensors, this book also provides a detailed overview of some of the advanced sensing methodologies based on photonic crystal cavity-based sensing devices. The authors showcase the extraordinary success of nanomaterials, their current strategical exploitation, and an unprecedented pool of possibilities they hold for the future.Many of the technologies have been developed recently for the sensing of various bioanalytes and molecules, some of which have been included in this book through dedicated chapters.The book looks at various sensors, such as for biosensing, electrochemical sensing, gas sensing, photoelectrochemical sensing, and colorimetric sensing, all of which have shown vast potential.

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  • Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules : Volume 651
    Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules : Volume 651

    Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules, Volume 651 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.Chapters in this new release include Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules, Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations, Electron Paramagnetic Resonance of Lanthanides, Characterization of lanthanoid binding proteins using NMR spectroscopy, Macromolecular crystallography for f-element complex characterization, Infrared spectroscopy probes ion binding geometries, Predicting lanthanide coordination structures in solution with molecular simulation, and much more. Additional sections cover the Characteristics of Gd(III) spin labels for the study of protein conformations, Lanthanide-based resonance energy transfer biosensors for live-cell applications, Yttrium-86 PET imaging, Aqueous Chemistry of the Smallest Rare Earth: Comprehensive Characterization of Radioactive and Non-radioactive Scandium Complexes for Biological Applications, and In vitro selection and application of lanthanide-dependent DNAzymes.

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  • Magneto-Optics and Spectroscopy of Antiferromagnets
    Magneto-Optics and Spectroscopy of Antiferromagnets

    Certain magnetic materials have optical properties that make them attractive for a wide variety of applications such as optical switches.This book describes the physics of one class of such magnetooptic materials, the insulating antiferromagnets.The authors summarize recent results concerning the structure, optical properties, spectroscopy, and magnetooptical properties of these materials.In particular, they consider magnetic phase transitions, symmetry effects, the linear magnetooptical effect, magnons, spectroscopic study of spin waves, photoinduced magnetic effects, and the effects of impurities.

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  • How is spectroscopy applied?

    Spectroscopy is applied in various fields such as chemistry, physics, astronomy, and environmental science. In chemistry, it is used to identify and analyze the chemical composition of substances. In physics, it is used to study the interaction of electromagnetic radiation with matter. In astronomy, it is used to determine the composition, temperature, and motion of celestial objects. In environmental science, it is used to monitor air and water quality by analyzing the presence of pollutants. Overall, spectroscopy is a versatile tool for analyzing the properties of different materials and substances.

  • Is it possible to create new materials through lower dimensional levels by using femtotechnology instead of nanotechnology?

    Femtotechnology operates at the scale of femtometers (10^-15 meters), which is smaller than the scale of nanotechnology (10^-9 meters). At this scale, it is theoretically possible to manipulate individual atomic nuclei and electrons to create entirely new materials with unique properties. By harnessing the power of femtotechnology, scientists may be able to engineer materials with unprecedented strength, conductivity, and other desirable characteristics. However, femtotechnology is still largely theoretical and has not yet been realized in practical applications, so its potential for creating new materials through lower dimensional levels remains speculative.

  • Why is Rutherford's scattering experiment called a scattering experiment at all?

    Rutherford's experiment is called a scattering experiment because it involved firing alpha particles at a thin gold foil and observing how they scattered after hitting the foil. The term "scattering" refers to the process of particles being deflected from their original path as a result of collisions with the atoms in the foil. By analyzing the pattern of scattering, Rutherford was able to deduce the structure of the atom and propose the existence of a dense, positively charged nucleus at its center. This experiment was crucial in advancing our understanding of atomic structure and the behavior of subatomic particles.

  • What are the arguments against nanotechnology?

    Some arguments against nanotechnology include concerns about potential health and environmental risks, such as the unknown effects of nanoparticles on living organisms and ecosystems. There are also ethical concerns related to the potential misuse of nanotechnology for military purposes or surveillance. Additionally, there are worries about the unequal distribution of benefits and risks, with some groups potentially being disproportionately affected by the consequences of nanotechnology development.

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